Mouse Egr2 activation kit by CRISPRa

CAT#: GA201203

Egr2 CRISPRa kit - CRISPR gene activation of mouse early growth response 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Egr2
• Locus ID: 13654
• Kit Components:

  GA201203G1, Egr2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201203G2, Egr2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201203G3, Egr2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001347458, NM_010118
• UniProt ID: P08152
• Synonyms: Egr-2; Krox-20; Krox20; NGF1-B; Zfp-6; Zfp-25
• Summary: Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes.[UniProtKB/Swiss-Prot Function]