Mouse Dpm2 activation kit by CRISPRa

CAT#: GA201120

Dpm2 CRISPRa kit - CRISPR gene activation of mouse dolichol-phosphate (beta-D) mannosyltransferase 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Dpm2
• Locus ID: 13481
• Kit Components:

  GA201120G1, Dpm2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201120G2, Dpm2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201120G3, Dpm2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010073
• UniProt ID: Q9Z324
• Synonyms: AW557993; R75484
• Summary: Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity).[UniProtKB/Swiss-Prot Function]