Mouse Cacnb2 activation kit by CRISPRa

CAT#: GA200484

Cacnb2 CRISPRa kit - CRISPR gene activation of mouse calcium channel, voltage-dependent, beta 2 subunit

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Cacnb2
• Locus ID: 12296
• Kit Components:

  GA200484G1, Cacnb2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200484G2, Cacnb2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200484G3, Cacnb2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252533, NM_001309519, NM_023116, NR_045533
• UniProt ID: Q8CC27
• Synonyms: AW060387; CAB2; Cavbeta2; Cchb2
• Summary: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.[UniProtKB/Swiss-Prot Function]