Mouse Bcl6b activation kit by CRISPRa

CAT#: GA200372

Bcl6b CRISPRa kit - CRISPR gene activation of mouse B cell CLL/lymphoma 6, member B

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Bcl6b
• Locus ID: 12029
• Kit Components:

  GA200372G1, Bcl6b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200372G2, Bcl6b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200372G3, Bcl6b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007528
• UniProt ID: O88282
• Synonyms: Bazf
• Summary: Acts as a sequence-specific transcriptional repressor in association with BCL6. Necessary for activation of naive T-cells to antigenic stimulation. May attenuate the regulatory effect of BCL6 on antigenic activation of naive CD4 T-cells by forming a heterodimer with BCL6.[UniProtKB/Swiss-Prot Function]