Mouse Chrnb2 activation kit by CRISPRa

CAT#: GA200036

Chrnb2 CRISPRa kit - CRISPR gene activation of mouse cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Chrnb2
• Locus ID: 11444
• Kit Components:

  GA200036G1, Chrnb2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200036G2, Chrnb2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200036G3, Chrnb2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009602
• UniProt ID: Q9ERK7
• Synonyms: Acrb-2; Acrb2; C030030P04Rik; [b]2-nAchR
• Summary: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.[UniProtKB/Swiss-Prot Function]