Human CEMP1 activation kit by CRISPRa

CAT#: GA119052

CEMP1 CRISPRa kit - CRISPR gene activation of human cementum protein 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CEMP1
• Locus ID: 752014
• Kit Components:

  GA119052G1, CEMP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA119052G2, CEMP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA119052G3, CEMP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001048212, NM_001048216
• UniProt ID: Q6PRD7
• Synonyms: CP-23; CP23
• Summary: May play a role in development of the periodontium which surrounds and supports the teeth by promoting the differentiation of multi-potent cells from the periodontal ligament into cementoblasts to form the cementum (PubMed:21929512, PubMed:17509525, PubMed:21465469). Binds hydroxyapatite and may promote the biomineralization of the cementum (PubMed:19393626). Also promotes cell proliferation (PubMed:17509525, PubMed:21929512, PubMed:26011628).[UniProtKB/Swiss-Prot Function]