Human PIM3 activation kit by CRISPRa

CAT#: GA118417

PIM3 CRISPRa kit - CRISPR gene activation of human Pim-3 proto-oncogene, serine/threonine kinase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PIM3
• Locus ID: 415116
• Kit Components:

  GA118417G1, PIM3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA118417G2, PIM3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA118417G3, PIM3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001852
• UniProt ID: Q86V86
• Synonyms: pim-3
• Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis. [provided by RefSeq, Jun 2012]