Human USP27X activation kit by CRISPRa

CAT#: GA118085

USP27X CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 27 X-linked

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: USP27X
• Locus ID: 389856
• Kit Components:

  GA118085G1, USP27X gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA118085G2, USP27X gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA118085G3, USP27X gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145073
• UniProt ID: A6NNY8
• Synonyms: USP22L; USP27
• Summary: This gene encodes a member of the peptidase protein family. The encoded protein functions as a deubiquitinase that is involved in upregulation of the pro-apoptotic Bim protein. This protein may act as a tumor suppressor by increasing levels of Bim to counteract anti-apoptotic signals in cancer cells. Mutations in this gene have been associated with X-linked cognitive disability. [provided by RefSeq, Dec 2016]