Human C4orf52 (SMIM20) activation kit by CRISPRa

CAT#: GA118037

SMIM20 CRISPRa kit - CRISPR gene activation of human small integral membrane protein 20

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SMIM20
• Locus ID: 389203
• Kit Components:

  GA118037G1, C4orf52 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA118037G2, C4orf52 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA118037G3, C4orf52 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145432
• UniProt ID: Q8N5G0
• Synonyms: C4orf52
• Summary: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Promotes the progression of complex assembly after the association of MT-CO1/COX1 with COX4I1 and COX6C. Chaperone-like assembly factor required to stabilize newly synthesized MT-CO1/COX1 and to prevent its premature turnover.[UniProtKB/Swiss-Prot Function]