Human SLC6A17 activation kit by CRISPRa

CAT#: GA117987

SLC6A17 CRISPRa kit - CRISPR gene activation of human solute carrier family 6 member 17

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SLC6A17
• Locus ID: 388662
• Kit Components:

  GA117987G1, SLC6A17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117987G2, SLC6A17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117987G3, SLC6A17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001010898
• UniProt ID: Q9H1V8
• Synonyms: MRT48; NTT4
• Summary: The protein encoded by this gene is a member of the SLC6 family of transporters, which are responsible for the presynaptic uptake of most neurotransmitters. The encoded vesicular transporter is selective for proline, glycine, leucine and alanine. In mouse, the strongest expression of this gene was in cortical and hippocampal tissues where expression increased during embryonic brain development and peaked postnatally. Defects in this gene cause a form of autosomal recessive intellectual disability. [provided by RefSeq, Jul 2017]