Human RGS9BP activation kit by CRISPRa

CAT#: GA117961

RGS9BP CRISPRa kit - CRISPR gene activation of human regulator of G protein signaling 9 binding protein

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: RGS9BP
• Locus ID: 388531
• Kit Components:

  GA117961G1, RGS9BP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117961G2, RGS9BP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117961G3, RGS9BP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_207391
• UniProt ID: Q6ZS82
• Synonyms: PERRS; R9AP; RGS9
• Summary: The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia. [provided by RefSeq, Mar 2010]