Human CLEC18A activation kit by CRISPRa

CAT#: GA117675

CLEC18A CRISPRa kit - CRISPR gene activation of human C-type lectin domain family 18 member A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CLEC18A
• Locus ID: 348174
• Kit Components:

  GA117675G1, CLEC18A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117675G2, CLEC18A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117675G3, CLEC18A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136214, NM_001271197, NM_182619, NM_001370523
• UniProt ID: A5D8T8
• Synonyms: MRCL; MRCL1; MRLP2
• Summary: This is one of three closely related paralogous genes on chromosome 16 encoding secreted proteins containing C-type lectin domains. These domains bind to carbohydrates in the presence of calcium, and may be involved in cell adhesion, immune response and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012]