Human ST8SIA6 activation kit by CRISPRa

CAT#: GA117375

ST8SIA6 CRISPRa kit - CRISPR gene activation of human ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ST8SIA6
• Locus ID: 338596
• Kit Components:

  GA117375G1, ST8SIA6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117375G2, ST8SIA6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117375G3, ST8SIA6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001004470, NM_001345961, NR_144322
• UniProt ID: P61647
• Synonyms: SIA8F; SIAT8-F; SIAT8F; ST8SIA-VI; ST8SiaVI
• Summary: This gene encodes a member of the glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]