Human ATG9B activation kit by CRISPRa

CAT#: GA117268

ATG9B CRISPRa kit - CRISPR gene activation of human autophagy related 9B

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ATG9B
• Locus ID: 285973
• Kit Components:

  GA117268G1, ATG9B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117268G2, ATG9B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117268G3, ATG9B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317056, NM_173681, NR_073169, NR_133652
• UniProt ID: Q674R7
• Synonyms: APG9L2; NOS3AS; SONE
• Summary: This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]