Human C6orf130 (OARD1) activation kit by CRISPRa

CAT#: GA116618

OARD1 CRISPRa kit - CRISPR gene activation of human O-acyl-ADP-ribose deacylase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: OARD1
• Locus ID: 221443
• Kit Components:

  GA116618G1, C6orf130 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116618G2, C6orf130 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116618G3, C6orf130 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329684, NM_001329685, NM_001329686, NM_001329688, NM_001329689, NM_001329690, NM_001329691, NM_001329692, NM_001329693, NM_001329694, NM_001329695, NM_001329696, NM_145063, NR_138080
• UniProt ID: Q9Y530
• Synonyms: C6orf130; dJ34B21.3; TARG1
• Summary: The protein encoded by this gene is a deacylase that can convert O-acetyl-ADP-ribose to ADP-ribose and acetate, O-propionyl-ADP-ribose to ADP-ribose and propionate, and O-butyryl-ADP-ribose to ADP-ribose and butyrate. The ADP-ribose product is able to inhibit these reactions through a competitive feedback loop. [provided by RefSeq, Jul 2016]