Human PATL1 activation kit by CRISPRa

CAT#: GA116549

PATL1 CRISPRa kit - CRISPR gene activation of human PAT1 homolog 1, processing body mRNA decay factor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PATL1
• Locus ID: 219988
• Kit Components:

  GA116549G1, PATL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116549G2, PATL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116549G3, PATL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152716
• UniProt ID: Q86TB9
• Synonyms: hPat1b; Pat1b
• Summary: RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).[UniProtKB/Swiss-Prot Function]