Human ARMC3 activation kit by CRISPRa

CAT#: GA116508

ARMC3 CRISPRa kit - CRISPR gene activation of human armadillo repeat containing 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ARMC3
• Locus ID: 219681
• Kit Components:

  GA116508G1, ARMC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116508G2, ARMC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116508G3, ARMC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282745, NM_001282746, NM_001282747, NM_173081
• UniProt ID: Q5W041
• Synonyms: CT81; KU-CT-1
• Summary: Armadillo/beta-catenin (CTNNB1; MIM 116806)-like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis (Li et al., 2006 [PubMed 16915934]).[supplied by OMIM, Mar 2008]