Human TMEM178 (TMEM178A) activation kit by CRISPRa

CAT#: GA115124

TMEM178A CRISPRa kit - CRISPR gene activation of human transmembrane protein 178A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TMEM178A
• Locus ID: 130733
• Kit Components:

  GA115124G1, TMEM178 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115124G2, TMEM178 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115124G3, TMEM178 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001167959, NM_152390
• UniProt ID: Q8NBL3
• Synonyms: TMEM178
• Summary: Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1.[UniProtKB/Swiss-Prot Function]