Human TYW3 activation kit by CRISPRa

CAT#: GA114986

TYW3 CRISPRa kit - CRISPR gene activation of human tRNA-yW synthesizing protein 3 homolog

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TYW3
• Locus ID: 127253
• Kit Components:

  GA114986G1, TYW3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114986G2, TYW3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114986G3, TYW3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001162916, NM_138467, NR_027962
• UniProt ID: Q6IPR3
• Synonyms: C1orf171
• Summary: Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]