Human ARHGAP12 activation kit by CRISPRa

CAT#: GA114335

ARHGAP12 CRISPRa kit - CRISPR gene activation of human Rho GTPase activating protein 12

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ARHGAP12
• Locus ID: 94134
• Kit Components:

  GA114335G1, ARHGAP12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114335G2, ARHGAP12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114335G3, ARHGAP12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270695, NM_001270696, NM_001270697, NM_001270698, NM_001270699, NM_018287
• UniProt ID: Q8IWW6
• Summary: This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]