Human MCU activation kit by CRISPRa

CAT#: GA114034

MCU CRISPRa kit - CRISPR gene activation of human mitochondrial calcium uniporter

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MCU
• Locus ID: 90550
• Kit Components:

  GA114034G1, MCU gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114034G2, MCU gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114034G3, MCU gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270679, NM_001270680, NM_138357, NR_073062
• UniProt ID: Q8NE86
• Synonyms: C10orf42; CCDC109A; HsMCU
• Summary: This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]