Human PPAPDC1B (PLPP5) activation kit by CRISPRa

CAT#: GA113572

PLPP5 CRISPRa kit - CRISPR gene activation of human phospholipid phosphatase 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PLPP5
• Locus ID: 84513
• Kit Components:

  GA113572G1, PPAPDC1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113572G2, PPAPDC1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113572G3, PPAPDC1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001102559, NM_001102560, NM_032483, NM_001354452, NM_001354454, NM_001354456, NM_001354457, NM_001354458, NM_001354459, NR_148893, NR_148894
• UniProt ID: Q8NEB5
• Synonyms: DPPL1; HTPAP; PPAPDC1B
• Summary: Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma.[UniProtKB/Swiss-Prot Function]