Human KIAA1712 (CEP44) activation kit by CRISPRa

CAT#: GA112987

CEP44 CRISPRa kit - CRISPR gene activation of human centrosomal protein 44

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CEP44
• Locus ID: 80817
• Kit Components:

  GA112987G1, KIAA1712 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112987G2, KIAA1712 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112987G3, KIAA1712 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001040157, NM_001145314, NM_030633
• UniProt ID: Q9C0F1
• Synonyms: KIAA1712; PS1TP3
• Summary: Centriole-enriched microtubule-binding protein involved in centriole biogenesis. In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall (PubMed:32060285). Functions as a linker component that maintains centrosome cohesion. Associates with CROCC and regulates its stability and localization to the centrosome (PubMed:31974111).[UniProtKB/Swiss-Prot Function]