Human SIKE1 activation kit by CRISPRa

CAT#: GA112833

SIKE1 CRISPRa kit - CRISPR gene activation of human suppressor of IKBKE 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SIKE1
• Locus ID: 80143
• Kit Components:

  GA112833G1, SIKE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112833G2, SIKE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112833G3, SIKE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001102396, NM_025073, NR_049741, NR_049742
• UniProt ID: Q9BRV8
• Synonyms: SIKE
• Summary: SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008]