Human Gasdermin D (GSDMD) activation kit by CRISPRa

CAT#: GA112629

GSDMD CRISPRa kit - CRISPR gene activation of human gasdermin D

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GSDMD
• Locus ID: 79792
• Kit Components:

  GA112629G1, Gasdermin D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112629G2, Gasdermin D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112629G3, Gasdermin D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166237, NM_024736
• UniProt ID: P57764
• Synonyms: DF5L; DFNA5L; FKSG10; GSDMDC1
• Summary: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]