Human NEIL1 activation kit by CRISPRa

CAT#: GA112528

NEIL1 CRISPRa kit - CRISPR gene activation of human nei like DNA glycosylase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NEIL1
• Locus ID: 79661
• Kit Components:

  GA112528G1, NEIL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112528G2, NEIL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112528G3, NEIL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256552, NM_024608, NR_046311, NM_001352519, NM_001352520
• UniProt ID: Q96FI4
• Synonyms: FPG1; hFPG1; NEI1
• Summary: This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]