Human ULBP3 activation kit by CRISPRa

CAT#: GA112449

ULBP3 CRISPRa kit - CRISPR gene activation of human UL16 binding protein 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ULBP3
• Locus ID: 79465
• Kit Components:

  GA112449G1, ULBP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112449G2, ULBP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112449G3, ULBP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024518
• UniProt ID: Q9BZM4
• Synonyms: RAET1N
• Summary: The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics. [provided by RefSeq, Nov 2015]