Human DEPTOR activation kit by CRISPRa

CAT#: GA112155

DEPTOR CRISPRa kit - CRISPR gene activation of human DEP domain containing MTOR interacting protein

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: DEPTOR
• Locus ID: 64798
• Kit Components:

  GA112155G1, DEPTOR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112155G2, DEPTOR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112155G3, DEPTOR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001283012, NM_022783
• UniProt ID: Q8TB45
• Synonyms: DEP.6; DEPDC6
• Summary: Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.[UniProtKB/Swiss-Prot Function]