Human USP36 activation kit by CRISPRa

CAT#: GA111625

USP36 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 36

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: USP36
• Locus ID: 57602
• Kit Components:

  GA111625G1, USP36 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111625G2, USP36 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111625G3, USP36 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001321291, NM_025090
• UniProt ID: Q9P275
• Synonyms: DUB1
• Summary: This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016]