Human PRR12 activation kit by CRISPRa

CAT#: GA111524

PRR12 CRISPRa kit - CRISPR gene activation of human proline rich 12

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PRR12
• Locus ID: 57479
• Kit Components:

  GA111524G1, PRR12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111524G2, PRR12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111524G3, PRR12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020719
• UniProt ID: Q9ULL5
• Synonyms: KIAA1205
• Summary: This gene encodes a proline-rich protein that contains two A-T hook DNA binding domains. A chromosomal translocation and gene fusion between this gene and zinc finger, MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient. Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development. [provided by RefSeq, Jul 2016]