Human RPRM activation kit by CRISPRa

CAT#: GA111189

RPRM CRISPRa kit - CRISPR gene activation of human reprimo, TP53 dependent G2 arrest mediator homolog

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: RPRM
• Locus ID: 56475
• Kit Components:

  GA111189G1, RPRM gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111189G2, RPRM gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111189G3, RPRM gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019845
• UniProt ID: Q9NS64
• Synonyms: REPRIMO
• Summary: May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity).[UniProtKB/Swiss-Prot Function]