Human TEX15 activation kit by CRISPRa

CAT#: GA111140

TEX15 CRISPRa kit - CRISPR gene activation of human testis expressed 15, meiosis and synapsis associated

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TEX15
• Locus ID: 56154
• Kit Components:

  GA111140G1, TEX15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111140G2, TEX15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111140G3, TEX15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_031271, NM_001350162, NR_146525
• Synonyms: CT42
• Summary: This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene stage. Naturally occurring mutations in this gene are associated with nonobstructive azoospermia. [provided by RefSeq, Apr 2017]