Human CISD1 activation kit by CRISPRa

CAT#: GA111016

CISD1 CRISPRa kit - CRISPR gene activation of human CDGSH iron sulfur domain 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CISD1
• Locus ID: 55847
• Kit Components:

  GA111016G1, CISD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111016G2, CISD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111016G3, CISD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018464
• UniProt ID: Q9NZ45
• Synonyms: C10orf70; MDS029; mitoNEET; ZCD1
• Summary: This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]