Human RNPC3 activation kit by CRISPRa

CAT#: GA110810

RNPC3 CRISPRa kit - CRISPR gene activation of human RNA binding region (RNP1, RRM) containing 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: RNPC3
• Locus ID: 55599
• Kit Components:

  GA110810G1, RNPC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110810G2, RNPC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110810G3, RNPC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017619
• UniProt ID: Q96LT9
• Synonyms: RBM40; RNP; SNRNP65
• Summary: Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]