Human DHTKD1 activation kit by CRISPRa

CAT#: GA110775

DHTKD1 CRISPRa kit - CRISPR gene activation of human dehydrogenase E1 and transketolase domain containing 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: DHTKD1
• Locus ID: 55526
• Kit Components:

  GA110775G1, DHTKD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110775G2, DHTKD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110775G3, DHTKD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018706
• UniProt ID: Q96HY7
• Synonyms: AMOXAD; CMT2Q
• Summary: This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013]