Human WDR33 activation kit by CRISPRa

CAT#: GA110718

WDR33 CRISPRa kit - CRISPR gene activation of human WD repeat domain 33

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: WDR33
• Locus ID: 55339
• Kit Components:

  GA110718G1, WDR33 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110718G2, WDR33 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110718G3, WDR33 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001006622, NM_001006623, NM_018383
• UniProt ID: Q9C0J8
• Synonyms: NET14; WDC146
• Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]