Human DCUN1D2 activation kit by CRISPRa

CAT#: GA110606

DCUN1D2 CRISPRa kit - CRISPR gene activation of human defective in cullin neddylation 1 domain containing 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: DCUN1D2
• Locus ID: 55208
• Kit Components:

  GA110606G1, DCUN1D2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110606G2, DCUN1D2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110606G3, DCUN1D2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001014283, NM_018185
• UniProt ID: Q6PH85
• Synonyms: C13orf17
• Summary: Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.[UniProtKB/Swiss-Prot Function]