Human RNF125 activation kit by CRISPRa

CAT#: GA110390

RNF125 CRISPRa kit - CRISPR gene activation of human ring finger protein 125

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: RNF125
• Locus ID: 54941
• Kit Components:

  GA110390G1, RNF125 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110390G2, RNF125 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110390G3, RNF125 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017831
• UniProt ID: Q96EQ8
• Synonyms: TNORS; TRAC-1; TRAC1
• Summary: This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012]