Human TTC19 activation kit by CRISPRa

CAT#: GA110357

TTC19 CRISPRa kit - CRISPR gene activation of human tetratricopeptide repeat domain 19

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TTC19
• Locus ID: 54902
• Kit Components:

  GA110357G1, TTC19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110357G2, TTC19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110357G3, TTC19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271420, NM_017775, NR_037985
• UniProt ID: Q6DKK2
• Synonyms: 2010204O13Rik; MC3DN2
• Summary: This gene encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each. These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions. This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III. It has also been suggested that this protein plays a role in cytokinesis. Mutations in this gene cause mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2012]