Human DNAJB11 activation kit by CRISPRa

CAT#: GA109961

DNAJB11 CRISPRa kit - CRISPR gene activation of human DnaJ heat shock protein family (Hsp40) member B11

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: DNAJB11
• Locus ID: 51726
• Kit Components:

  GA109961G1, DNAJB11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109961G2, DNAJB11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109961G3, DNAJB11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016306
• UniProt ID: Q9UBS4
• Synonyms: ABBP-2; ABBP2; Dj-9; DJ9; EDJ; ERdj3; ERj3; ERj3p; PRO1080; UNQ537
• Summary: This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity. [provided by RefSeq, Mar 2014]