Human LUC7L2 activation kit by CRISPRa

CAT#: GA109910

LUC7L2 CRISPRa kit - CRISPR gene activation of human LUC7 like 2, pre-mRNA splicing factor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: LUC7L2
• Locus ID: 51631
• Kit Components:

  GA109910G1, LUC7L2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109910G2, LUC7L2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109910G3, LUC7L2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244585, NM_001270643, NM_016019
• UniProt ID: Q9Y383
• Synonyms: CGI-59; CGI-74; LUC7B2
• Summary: This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]