Human SCLY activation kit by CRISPRa

CAT#: GA109863

SCLY CRISPRa kit - CRISPR gene activation of human selenocysteine lyase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SCLY
• Locus ID: 51540
• Kit Components:

  GA109863G1, SCLY gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109863G2, SCLY gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109863G3, SCLY gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016510
• UniProt ID: Q96I15
• Synonyms: hSCL; SCL
• Summary: Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008]