Human JKAMP activation kit by CRISPRa

CAT#: GA109854

JKAMP CRISPRa kit - CRISPR gene activation of human JNK1/MAPK8 associated membrane protein

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: JKAMP
• Locus ID: 51528
• Kit Components:

  GA109854G1, JKAMP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109854G2, JKAMP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109854G3, JKAMP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001098625, NM_001284201, NM_001284202, NM_001284203, NM_001284204, NM_016475
• UniProt ID: Q9P055
• Synonyms: C14orf100; CDA06; HSPC213; HSPC327; JAMP
• Summary: May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (By similarity).[UniProtKB/Swiss-Prot Function]