Human CXXC5 activation kit by CRISPRa

CAT#: GA109850

CXXC5 CRISPRa kit - CRISPR gene activation of human CXXC finger protein 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CXXC5
• Locus ID: 51523
• Kit Components:

  GA109850G1, CXXC5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109850G2, CXXC5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109850G3, CXXC5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317199, NM_001317200, NM_001317201, NM_001317202, NM_001317203, NM_001317204, NM_001317205, NM_001317206, NM_001317207, NM_001317208, NM_001317209, NM_001317210, NM_001317211, NM_016463
• UniProt ID: Q7LFL8
• Synonyms: CF5; HSPC195; RINF; WID
• Summary: The protein encoded by this gene is a retinoid-inducible nuclear protein containing a CXXC-type zinc finger motif. The encoded protein is involved in myelopoiesis, is required for DNA damage-induced p53 activation, regulates the differentiation of C2C12 myoblasts into myocytes, and negatively regulates cutaneous wound healing. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015]