Human NAT8B activation kit by CRISPRa

CAT#: GA109822

NAT8B CRISPRa kit - CRISPR gene activation of human N-acetyltransferase 8B (putative, gene/pseudogene)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NAT8B
• Locus ID: 51471
• Kit Components:

  GA109822G1, NAT8B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109822G2, NAT8B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109822G3, NAT8B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016347, NR_132338
• UniProt ID: Q9UHF3
• Synonyms: CML2; Hcml2; NAT8BP
• Summary: The protein encoded by this gene is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8. [provided by RefSeq, Jul 2008]