Human CLEC1 (CLEC1A) activation kit by CRISPRa

CAT#: GA109690

CLEC1A CRISPRa kit - CRISPR gene activation of human C-type lectin domain family 1 member A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CLEC1A
• Locus ID: 51267
• Kit Components:

  GA109690G1, CLEC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109690G2, CLEC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109690G3, CLEC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001297748, NM_001297749, NM_001297750, NM_001297751, NM_016511
• UniProt ID: Q8NC01
• Synonyms: CLEC-1; CLEC1
• Summary: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]