Human HSD17B14 activation kit by CRISPRa

CAT#: GA109623

HSD17B14 CRISPRa kit - CRISPR gene activation of human hydroxysteroid 17-beta dehydrogenase 14

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: HSD17B14
• Locus ID: 51171
• Kit Components:

  GA109623G1, HSD17B14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109623G2, HSD17B14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109623G3, HSD17B14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016246
• UniProt ID: Q9BPX1
• Synonyms: DHRS10; retSDR3; SDR47C1
• Summary: 17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]