Human EXOSC3 activation kit by CRISPRa

CAT#: GA109494

EXOSC3 CRISPRa kit - CRISPR gene activation of human exosome component 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: EXOSC3
• Locus ID: 51010
• Kit Components:

  GA109494G1, EXOSC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109494G2, EXOSC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109494G3, EXOSC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002269, NM_016042
• UniProt ID: Q9NQT5
• Synonyms: bA3J10.7; CGI-102; hRrp-40; p10; PCH1B; RRP40; Rrp40p
• Summary: This gene encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2012]