Human MYCBP activation kit by CRISPRa

CAT#: GA108851

MYCBP CRISPRa kit - CRISPR gene activation of human MYC binding protein

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MYCBP
• Locus ID: 26292
• Kit Components:

  GA108851G1, MYCBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108851G2, MYCBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108851G3, MYCBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012333, NR_037632
• UniProt ID: Q99417
• Synonyms: AMY-1
• Summary: The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011]