Human LCE2B activation kit by CRISPRa

CAT#: GA108812

LCE2B CRISPRa kit - CRISPR gene activation of human late cornified envelope 2B

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: LCE2B
• Locus ID: 26239
• Kit Components:

  GA108812G1, LCE2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108812G2, LCE2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108812G3, LCE2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014357
• UniProt ID: O14633
• Synonyms: LEP10; SPRL1B; XP5
• Summary: This gene is one of the at least 20 genes expressed during epidermal differentiation and located on chromosomal band 1q21. This gene is involved in epidermal differentiation, and it is expressed at high levels in normal and psoriatic skin, but not in cultured keratinocytes or in any other tested cell types or tissues. [provided by RefSeq, Jul 2008]